Milan will face three of last season s other top-six sides in their opening seven games of the 2021-22 Serie A campaign.
Last season s second-placed finish was the Rossoneri s best in nine years, but it was tinged with disappointment as bitter rivals Inter overtook them to finish at the summit.
Stefano Pioli s men will be looking to go one better this time around and end their 11-season wait for Scudetto glory, though they have been dealt a difficult hand.
Milan take on Sampdoria and Cagliari in their opening two matches, before a tough run that will see them face Lazio, Juventus and Atalanta within their next five games.
The first Derby della Madonnina of the season will take place on matchday 12 in early November, with Milan the designated home team for that showdown with champions Inter.
The reverse fixture in the opening week of February comes straight on the back of a home match against Juventus, who are being coached once again this term by ex-Milan boss Massimiliano Allegri.
Milan face Atalanta in their final home match of 2020-21 before heading to Sassuolo in the concluding round of games.
2021/22
Ready for the new season? Here s the full fixture list
Pronti per la nuova ? Ecco il calendario completo
— AC Milan (@acmilan)
Milan s Serie A fixtures in full, subject to change:
22/08/2021 Sampdoria (a)
29/08/2021 Cagliari (h)
12/09/2021 Lazio (h)
19/09/2021 Juventus (a)
22/09/2021 Venezia (h)
25/09/2021 Spezia (a)
03/10/2021 Atalanta (a)
17/10/2021 Hellas Verona (h)
24/10/2021 Bologna (a)
27/10/2021 Torino (h)
31/10/2021 Roma (a)
07/11/2021 Inter (h)
21/11/2021 Fiorentina (a)
28/11/2021 Sassuolo (h)
01/12/2021 Genoa (a)
05/12/2021 Salernitana (h)
12/12/2021 Udinese (a)
19/12/2021 Napoli (h)
22/12/2021 Empoli (a)
06/01/2022 Roma (h)
09/01/2022 Venezia (a)
16/01/2022 Spezia (h)
23/01/2022 Juventus (h)
06/02/2022 Inter (a)
13/02/2022 Sampdoria (h)
20/02/2022 Salernitana (a)
27/02/2022 Udinese (h)
06/03/2022 Napoli (a)
13/03/2022 Empoli (h)
20/03/2022 Cagliari (a)
03/04/2022 Bologna (h)
10/04/2022 Torino (a)
16/04/2022 Genoa (h)
24/04/2022 Lazio (a)
01/05/2022 Fiorentina (h)
08/05/2022 Hellas Verona (a)
15/05/2022 Atalanta (h)
22/05/2022 Sassuolo (a)